Abstrak
Penyakit ginjal kronis (PGK) masih menjadi masalah kesehatan global. Riset Kesehatan Dasar (Riskesdas) menunjukkan peningkatan prevalensi PGK di Indonesia dari 0,2 menjadi 0,38 % (2013-2018). Hemodialisis (HD) merupakan salah satu modalitas terapi pengganti ginjal pada penyakit ginjal kronik tahap akhir (PGTA). Efusi pleura sering dijumpai pada pasien PGTA yang menjalani HD. Pada PGTA yang belum HD terdapat 3% efusi pleura dan 31,85% yang telah menjalani HD. Mekanisme efusi pleura pada PGTA dianggap berkaitan erat dengan kondisi kelebihan cairan dan HD yang tidak optimal. N-terminal prohormone-brain natriuretic peptide (NT-proBNP) dianggap dapat mendeteksi kondisi kelebihan cairan dan evaluasi adekuasi HD berkala perlu dilakukan pada pasien HD. Karena itu, peneliti tertarik untuk meneliti bagaimana hubungan Adekuasi Hemodialisis dan Kadar NT-proBNP terhadap jenis Efusi Pleura Pada Pasien PGK. Penelitian bersifat analitik dengan pendekatan cross sectional dan menggunakan total sampling mulai 1 April 2024 hingga 31 Juli 2024 yang dilakukan di RSUD dr. Zainoel Abidin Banda Aceh. Penelitian ini melibatkan pasien efusi pleura yang menjalani HD di RSUZA. Variabel bebas pada penelitian ini adalah Adekuasi HD (Kt/V) dan Kadar NT-proBNP dan variabel terikat Efusi Pleura. Uji normalitas menggunakan Shapiro wilk. Hubungan antar variabel diuji menggunakan Pearson correlation test bila distribusi data normal atau uji Spearman correlation test distribusi data tidak normal. Hasil penelitian menunjukkan NT-proBNP memiliki hubungan yang signifikan terhadap Efusi Pleura Transudat dengan nilai p=0,762 di tingkat kepercayaan 99%. Adekuasi HD tidak memiliki hubungan yang signifikan terhadap efusi pleura transudat dengan nilai p= -0,134.
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