Keywords
total laringektomi
diseksi leher
angka kesintasan
How to Cite
Abstract
Pilihan terapi untuk karsinoma laring yang progresif (T3-T4) adalah operasi, baik untuk tumor laring maupun diseksi nodul pada leher, yang setelah itu dilanjutkan dengan kemoterapi, radiasi atau kombinasi kemoradiasi. Diseksi nodul pada leher dilakukan sesuai stadium penyakit. Sebagian besar pasien yang terdiagnosis pada stadium lanjut atau metastasis nodal regional, umumnya memiliki tingkat kelangsungan hidup 50%. Penelitian ini bertujuan menganalisis perbedaan angka kesintasan pasien dengan karsinoma laring yang telah menjalani total laringektomi dengan atau tanpa diseksi leher. Pengumpulan data menggunakan rekam medis pasien yang berobat ke Departemen THT-BKL RSUD dr. Zainoel Abidin sejak 1 Juli–30 September 2022. Metode penelitian berupa analitik observasional retrospektif dengan desain khusus analisis kesintasan, Diperoleh total 36 subjek, seluruhnya laki-laki, terbanyak (47,2%) pada kelompok usia 56-65 tahun. Mayoritas subjek (97,2%) memiliki riwayat merokok lebih dari 30 tahun, dengan 44,4% lokasi tumor berada di transglotis, dan pasien terbanyak (88,9%) datang ke rumah sakit pada stadium IV, secara histopatologi 75% jenis keratinizing squamous cell carsinoma. Sejumlah 41,7% menjalani total laringektomi saja dan 58,3% menjalani total laringektomi disertai diseksi leher. Hasil analisis kurva Kaplan Meier didapatkan angka bertahan hidup pada total laringektomi rata-rata 33,24 bulan dan 34,29 bulan pada total laringektomi dengan diseksi leher. Penelitian menunjukkan tidak terdapat perbedaan signifikan pada angka kesintasan pasien karsinoma laring yang menjalani total laringektomi dengan dan tanpa diseksi leher.
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